This is the first version of the 2025–26 General Catalog. Please check back regularly for changes. The final edition and the historical PDF will be published during the fall semester.
Program Competencies
Graduates will be able to:
- discuss issues related to biomedical informatics impacting clinical research;
- summarize requirements for building and maintaining a multidisciplinary research team;
- describe health and disease measurement in clinical and community populations;
- describe how to implement a clinical research study;
- develop a clinical research question;
- apply principles of responsible research and clinical research ethics to a research project;
- determine a study aim, objectives, and appropriate design to address a hypothesis;
- analyze epidemiologic data with descriptive analysis and regression models, including linear and logistic regression;
- analyze literature to identify gaps in knowledge; and
- communicate clinical research findings effectively.
The Master of Science in clinical investigation requires 37 s.h. of graduate credit. In addition to completing the program's required coursework, students must write a manuscript or a grant proposal for a National Institutes of Health (NIH) career award or its equivalent, with oral defense. Graduate students must maintain a Graduate College program grade-point average of at least 3.00. Those who receive a grade of C in 7 s.h. of coursework may be dismissed from the program.
The program, which is offered in collaboration with the university's Institute for Clinical and Translational Science, is designed for clinicians interested in pursuing careers in clinical research. It includes in-depth training in biostatistics, epidemiology, research ethics, and academic survival skills as well as didactic training applicable to clinical research careers. Graduates of the program are able to critically evaluate clinical literature, write competitive grant proposals, design and conduct clinical research projects, work effectively with other researchers and support staff, and disseminate research results through manuscripts and presentations.
The MS in clinical investigation requires the following coursework.
Core Courses
All core courses except CPH:6100 and CPH:7270 must be taken on an A–F graded basis. Students must retake CPH:7270 if they completed the course more than four years ago or if they have changed degree programs.
| Course # | Title | Hours |
|---|---|---|
| All of these (25 s.h.): | ||
| BIOS:4120 | Introduction to Biostatistics | 3 |
| BIOS:5120 | Regression Modeling and ANOVA in the Health Sciences | 3 |
| EPID:4400 | Epidemiology I: Principles | 3 |
| EPID:5500 | Introduction to Clinical Epidemiology | 3 |
| EPID:5610 | Intermediate Epidemiology Data Analysis With SAS and R | 3 |
| EPID:6150 | Writing for Medical Journals | 1 |
| EPID:6400 | Epidemiology II: Advanced Methods | 4 |
| EPID:6950 | Clinical Research Ethics | 2 |
| CPH:6100 | Essentials of Public Health | 2 |
| CPH:7270 | Principles of Scholarly Integrity: Public Health (taken first year in the fall and spring semesters for 0 s.h. and 1 s.h., respectively) | 1 |
Capstone Requirement
While a student does not take a final examination of courses, the evaluation of the student for graduation is based upon a positive review of a mentored K or R grant or a mentored publishable research paper. The grant or paper is completed in the second year of the program and is based on the area of focus. The capstone is a mentored activity that requires approval by a clinical mentor and a Department of Epidemiology primary faculty member. Successful completion of the course is denoted with a satisfactory (S) grade. The complete grant or paper will be due no later than one month prior to graduation for review.
| Course # | Title | Hours |
|---|---|---|
| EPID:6000 | Independent Study in Epidemiology | 2 |
Electives
Students must earn a minimum of 10 s.h. in elective coursework from any of the following content areas.
| Course # | Title | Hours |
|---|---|---|
| Research Design and Communication | ||
| EPID:5214 | Meta-Analysis of Epidemiologic Studies | 3 |
| EPID:6100 | Writing a Grant Proposal | 3 |
| EPID:6900 | Design of Intervention and Clinical Trials | 3 |
| EPID:6910 | Pharmacoepidemiology and Comparative Effectiveness Research | 3 |
| Community Studies | ||
| CBH:5235 | Community-Based Participatory Research | 3 |
| CBH:5305 | Evaluation: Approaches and Applications | 3 |
| CBH:6205 | Designing and Implementing Interventions | 3 |
| EPLS:5165 | Introduction to Program and Project Evaluation | 3 |
| Epidemiology | ||
| EPID:5560 | Biomarkers in Epidemiology | 3 |
| EPID:5570 | Zoonotic Diseases | 3 |
| EPID:6510 | Injury Epidemiology | 3 |
| EPID:6550 | Epidemiology of Infectious Diseases | 3 |
| EPID:6560 | Hospital Epidemiology | 2 |
| EPID:6600 | Epidemiology of Chronic Diseases | 3 |
| DPH:6004 | Principles of Oral Epidemiology | 3 |
| SEES:3110 | Geography of Health | 3 |
| Health Services Epidemiology | ||
| EPID:6360 | Nutrition Intervention in Clinical Trials Research | 2 |
| EPID:6655 | Causal Inference | 3 |
| EPID:6920 | Applied Administrative Data Analysis | 2 |
| BIOS:6610 | Statistical Methods in Clinical Trials | 3 |
| BIOS:7600 | Advanced Biostatistics Seminar | 3 |
| PCOL:5136 | Pharmacogenetics and Pharmacogenomics | 1 |
| Informatics | ||
| EPID:5600 | Introduction to Epidemiology Data Management and Analysis | 3 |
| HMP:5315 | Health Information Systems | 3 |
| Nutrition Science | ||
| EPID:6330 | Global Nutrition Policy | 2-3 |
| EPID:6350 | Nutritional Epidemiology | 2 |
| EPID:6370 | Nutrition Intervention in Research Lab | 3 |
| Outcomes and Health Services Research | ||
| HMP:5410 | Health Economics I | 3 |
| HMP:7550 | Cost Effectiveness and Decision Analysis | 3 |
| HMP:7960 | Analytic Issues in Health Services Research I | 3 |
| HMP:7965 | Analytic Issues in Health Services Research II | 3 |
| Pharmacy Science | ||
| PHAR:5310 | Health Services Research Seminar | 1 |
| PHAR:5350 | Introduction to Research Methods | 3 |
| PHAR:6305 | Foundation Literature in Health Services Research | 3 |
| Statistical Methods | ||
| BIOS:6210 | Applied Survival Analysis | 3 |
| BIOS:6310 | Introductory Longitudinal Data Analysis | 3 |
| Translational Biomedicine | ||
| TBM:5001 | Introduction to Translational Biomedicine | 3 |
Applicants must apply through the Schools of Public Health Application Service (SOPHAS); they must also pay the required application fee to the Graduate College through University of Iowa Admissions when prompted. For detailed application information, visit How to Apply to the Department of Epidemiology on the department's website.
Applicants must hold a doctoral-level degree in a clinical discipline (e.g., MD, DO, DDS, PhD, PharmD, DVM) or be enrolled in the Medical Scientist Training Program (Carver College of Medicine). They must hold a baccalaureate degree with a cumulative grade-point average of at least 3.00; internationally trained applicants must have an outstanding doctoral training record evidenced by research publications.
Applicants are considered based on their credentials, prior training, and research training plans. Applicants with deficiencies in one area may be admitted if all other components of their application are strong. Individuals must have a sponsoring department.
Applicants must meet the admission requirements of the Graduate College; see the Manual of Rules and Regulations on the Graduate College website.
Application deadlines for fall admission are June 1 for U.S. citizens and April 15 for international applicants. For summer admission, the deadline is April 1; for spring admission, Dec. 1.
Prerequisites
The MS program requires at least 6 s.h. of prerequisite coursework in the disciplines of pathology, physiology, and/or pharmacology. Students accepted into the degree program who have not completed at least 6 s.h. from those disciplines may meet the requirement while they are enrolled.
Sample Plan of Study
Sample plans represent one way to complete a program of study. Actual course selection and sequence will vary and should be discussed with an academic advisor. For additional sample plans, see MyUI.
Clinical Investigation, MS
This sample plan is currently being reviewed and will be added at a later date.