University College is home to a wide range of programs for University of Iowa students and precollege students. It includes major college-level programs such as the University of Iowa Honors Program, Study Abroad, Career Center Programs, and study at Iowa Lakeside Laboratory.

University College offers programs leading to the Bachelor of Applied Studies (B.A.S.) degree and the Bachelor of Liberal Studies (B.L.S.) degree. Both programs enable students to complete a bachelor's degree by distance education. The B.A.S., which is designed for graduates of community college technical programs, provides alternatives to traditional academic majors, permitting students to plan their own emphasis areas in consultation with their advisors. The B.L.S. is a general undergraduate degree without a traditional academic major; students work with their advisors to plan study programs that meet their individual objectives.

The college also offers undergraduate certificates in clinical and translational science, leadership studies, nonprofit management, and sustainability. In addition, it is home to summer undergraduate research opportunities in the STEM fields (science, technology, engineering, and mathematics), microbiology, and medical scientist training.

Some University College programs and courses are designed to smooth entering students' transition to college life, such as College Success Initiatives courses and first-year seminars, or to provide opportunities for populations underrepresented in the sciences and engineering, such as the Iowa Biosciences Academy.

The Division of Continuing Education, in partnership with the University's colleges and departments, provides high quality credit and noncredit courses, workshops, and programs to traditional and nontraditional learners. The division administers a number of programs on campus.

Lifetime Leisure Skills courses offer a broad range of sports and fitness activities. The University's Reserve Officer Training Corps programs, Aerospace Studies (Air Force ROTC) and Military Science (Army ROTC), also reside in University College.

For undergraduate college students at Iowa State University or the University of Northern Iowa, the Regents Online Exchange offers the opportunity for students to access online courses at the University of Iowa that may not be available at their institutions.

University College offers courses in several K-12 programs: the Belin-Blank Center for Gifted Education, the Center for Diversity & Enrichment, Project Lead the Way (biomedical and health sciences), the Secondary Student Training Program, and University of Iowa Upward Bound.

Courses offered through University College are taught by University of Iowa faculty and staff members.