The Master of Science program in clinical investigation requires 30 s.h. of graduate credit. In addition to completing the program's required course work, M.S. students must write a thesis in the form of a manuscript, or a grant proposal for a National Institutes of Health (NIH) career award or its equivalent, with oral defense.

The program, which is offered in collaboration with the University's Institute for Clinical and Translational Science, is designed for clinicians interested in pursuing careers in clinical research. It includes in-depth training in biostatistics, epidemiology, research ethics, and academic survival skills as well as didactic training applicable to clinical research careers. Graduates of the program are able to critically evaluate clinical literature, write competitive grant proposals, design and conduct clinical research projects, work effectively with other researchers and support staff, and disseminate research results through manuscripts and presentations.

Applicants to the program must have completed the following course work.

BIOS:4120Introduction to Biostatistics3
EPID:4400Epidemiology I: Principles (or equivalent)3
Courses in pathology, physiology, and/or pharmacology6

Students who are admitted to the program with deficiencies in the required 6 s.h. of pathology, physiology, and/or pharmacology may complete courses that fulfill the requirement once they have enrolled in the program.

Graduate students in the Department of Epidemiology must maintain a g.p.a. of at least 3.00. Those who receive a grade of C in 7 s.h. of course work may be dismissed from the program.

The M.S. with a major in clinical investigation requires the following course work.

Core Courses

Students must complete all of the following core courses (20 s.h.).

EPID:5241Statistical Methods in Epidemiology4
EPID:5500Introduction to Clinical Epidemiology3
EPID:5610Intermediate Epidemiology Data Analysis with SAS and R3
EPID:6000Independent Study in Epidemiology2
EPID:6150Writing for Medical Journals1
EPID:6400Epidemiology II: Advanced Methods4
EPID:6950Clinical Research Ethics2
CPH:6100Essentials of Public Health1


Students must earn a minimum of 10 s.h. in elective course work, which must include at least 3 s.h. in focus area electives. In addition to the focus area electives, the following courses are recommended as elective course work.

EPID:5214Meta-Analysis of Epidemiologic Studies3
EPID:6100Writing a Grant Proposal3
EPID:6900Design of Intervention and Clinical Trials3

Focus Area Electives

Students must complete at least 3 s.h. chosen from the following focus area electives.

Health Services Epidemiology

EPID:4990Practicing Evidence-Based Public Health3
EPID:6360Nutrition Intervention in Clinical Trials Research2
EPID:6900Design of Intervention and Clinical Trials3
EPID:6920Applied Administrative Data Analysis2
BIOS:6610Statistical Methods in Clinical Trials3
BIOS:7600Advanced Biostatistics Seminar3
CBH:6205Designing and Implementing Interventions3
PCOL:5136Pharmacogenetics and Pharmacogenomics1
PHAR:7100Translational Research and Clinical Drug Development3

Nutrition Science

EPID:6330Global Nutrition Policy3
EPID:6350Nutritional Epidemiology2
EPID:6360Nutrition Intervention in Clinical Trials Research2
EPID:6370Nutrition Intervention in Research Lab3


EPID:5560Introduction to Molecular Epidemiology3
EPID:5570Zoonotic Diseases3
EPID:6250Genetics and Epidemiology3
EPID:6510Injury Epidemiology3
EPID:6530Epidemiology of Occupational Injuries3
EPID:6550Epidemiology of Infectious Diseases3
EPID:6560Hospital Epidemiology2
EPID:6600Epidemiology of Chronic Diseases3
EPID:6640Epidemiology of Maternal and Infant Health2
EPID:6650Cardiovascular Disease Epidemiology3
EPID:6670Psychiatric Epidemiology3
EPID:6700Cancer Epidemiology and Control3
DPH:6004Principles of Oral Epidemiology3
GEOG:3110Geography of Health3


EPID:4450Public Health Data2
EPID:5200Principles of Public Health Informatics3
EPID:5600Introduction to Epidemiology Data Management and Analysis3
HMP:5315Health Information Systems3
HMP:5370Health Informatics I3

Community Studies

CBH:5235Community-Based Participatory Research3
CBH:5305Evaluation: Approaches and Applications3
CBH:6205Designing and Implementing Interventions3
EPLS:5165Introduction to Program and Project Evaluation3

Statistical Methods

BIOS:6210Applied Survival Analysis3
BIOS:6310Introductory Longitudinal Data Analysis3

Outcomes and Health Services Research

HMP:5410Health Economics I3
HMP:7550Cost Effectiveness and Decision Analysis3
HMP:7960Analytic Issues in Health Services Research I3
HMP:7965Analytic Issues in Health Services Research II3

Pharmacy Science

PHAR:5310Pharmaceutical Socioeconomics Seminar1
PHAR:5350Introduction to Research Methods3
PHAR:6305Foundation Literature in Pharmaceutical Socioeconomics3

Applicants to the M.S. program in the Department of Epidemiology must apply through the Schools of Public Health Application Service (SOPHAS); they also must pay the required application fee to the Graduate College through the University of Iowa Office of Admissions when prompted. For detailed application information, visit How to Apply to the Department of Epidemiology web page.

Applicants to the M.S. program in clinical investigation must hold a doctoral-level degree in a clinical discipline (e.g., M.D., D.O., D.D.S., Ph.D., Pharm.D., D.V.M.) or be enrolled in the Medical Scientist Training Program (Carver College of Medicine). They must hold a baccalaureate degree with a cumulative g.p.a. of at least 3.00; foreign-trained applicants must have an outstanding doctoral training record evidenced by research publications.

Test of English as a Foreign Language (TOEFL) scores are required for international students except permanent residents or those who have earned a degree from an accredited institution in the United States, United Kingdom, Ireland, Canada (excluding French Quebec), English-speaking Africa, Australia, or New Zealand. The recommended minimum score is 100.

Applicants are considered based on their credentials, prior training, and research training plans. Applicants with deficiencies in one area may be admitted if all other components of their application are strong. Individuals must have a sponsoring department.

Applicants must meet the admission requirements of the Graduate College; see the Manual of Rules and Regulations of the Graduate College.

Application deadlines are June 1 for U.S. citizens, April 15 for international applicants.

A limited number of graduate research assistantships are available for advanced students; for information, consult the department. For information on financing education through jobs, grants, and loans, contact the University's Office of Student Financial Aid.

Opportunities for funded predoctoral fellowships are available. Funded positions sponsored by federal agencies are available only to U.S. citizens.