The goals of the M.S. program in translational biomedicine are to:

  • promote interaction and collaboration among researchers across the spectrum of biomedicine;
  • enrich translational vocabulary and an understanding of T1 research (laboratory), T2 research (application to evidence-based practice), T3 research (implementation and dissemination), and T4 research (population studies and policy development) among basic, clinical, and human studies scientists; and
  • develop skills in ethical decision making, scientific leadership, team building, networking, and research program management.

The Master of Science program in translational biomedicine (TBM) requires a minimum of 30 s.h. of graduate credit plus a final project. Students must maintain a cumulative graduate g.p.a. of at least 3.00 in all UI course work. The plan of study for students in the two-year program is based on their chosen discipline.

The program is designed to teach members of scientific teams how to move biomedical discoveries into clinical applications and beyond. It is tailored for individuals who have completed doctoral-level training in one area of biomedicine and wish to apply their expertise to the T1-T4 research spectrum. The program admits individuals who hold medical or graduate degrees (e.g., M.D., D.O., D.D.S., D.N.P., Ph.D., Pharm.D., D.V.M., or the equivalent) and are employed by the University of Iowa at the faculty ranks of associate professor, assistant professor, instructor, a fellow physician, or a postdoctoral scholar/fellow.

The M.S. with a major in translational biomedicine requires the following course work.

Core Courses

All of these:
TBM:5000Translational Biomedical Research9
TBM:5001Introduction to Translational Biomedicine3
TBM:5002Critical Thinking and Communication: Study Design and Commercialization1
TBM:5003Critical Thinking and Communication: Scientific Writing and Presentation Strategies1
TBM:5004Critical Thinking and Communication: Career Development and the Funding Process1
TBM:5005Critical Thinking and Communication: Leadership, Team Science, and Mentoring1
BIOS:4120Introduction to Biostatistics3
EPID:4400Epidemiology I: Principles3
EPID:6950Clinical Research Ethics2
Total Hours24

Electives

Students must earn a minimum of 6 s.h. in graduate-level elective course work pertinent to their educational goals and background. Electives may be selected from the lists below, or students may obtain approval for other courses with program administration approval.

Epidemiology

EPID:5241Statistical Methods in Epidemiology4
EPID:5500Introduction to Clinical Epidemiology3
EPID:5610Intermediate Epidemiology Data Analysis with SAS and R3
EPID:5900Problems and Special Topics in Epidemiologyarr.
EPID:6100Writing a Grant Proposal3
EPID:6150Writing for Medical Journals1
EPID:6250Genetics and Epidemiology3
EPID:6400Epidemiology II: Advanced Methods4
EPID:6650Cardiovascular Disease Epidemiology3
EPID:6900Design of Intervention and Clinical Trials3

Drug Discovery

BME:5330Computational Genomics3
PCOL:5136Pharmacogenetics and Pharmacogenomics1
PCOL:6250Advanced Problem Solving in Pharmacological Sciences1
PHAR:5512Drug Discovery and Mechanisms3

Innovation

ENTR:9400Evaluating Innovation Opportunities2-3
ENTR:9550Commercializing New Technology3
LAW:9717Iowa Medical Innovation Group Seminararr.
NURS:6553Seminar on Innovations4

Device Development

BME:5210Medical Imaging Physics3
BME:5220Digital Image Processing3
BME:5230Multidimensional Medical Imaging Process3
BME:5401Biomaterials and Implant Design3
BME:5510Cardiovascular Biomechanics3
BME:5520Cardiovascular Fluid Mechanics3
BME:5530Design of Circulatory Implants and Artificial Organs3
BME:5550Cardiovascular Tissue Mechanics3
BME:5610Musculoskeletal Biomechanics3

Neuroscience

NSCI:5210Fundamentals of Behavioral Neuroscience3-4
NSCI:5365Seminar: Neuropsychology and Neurosciencearr.
NSCI:5653Fundamental Neurobiology3
NSCI:5753Developmental Neuroscience1
NSCI:6250Functional Magnetic Resonance Imaging2-3
NSCI:7235Neurobiology of Disease3
PSY:6280Structural and Functional MRI Methods and Application3
PSY:6370Principles of Neuropsychology3

Genetics

ACB:6200Special Topics in Genetics1
BME:5330Computational Genomics3
GENE:5173Computational Genomics3
GENE:6150Genetic Analysis of Biological Systems3
GENE:6234Basic Biostatistical Methods with Genetics Applications1
GENE:7191Human Molecular Genetics3

Informatics and Biostatistics

BIOS:5120Regression Modeling and ANOVA in the Health Sciences3
BIOS:5510Biostatistical Computing2
BIOS:5710Biostatistical Methods I4
BIOS:5720Biostatistical Methods II4
BIOS:5730Biostatistical Methods in Categorical Data3
BIOS:6110Applied Categorical Data Analysis3
BIOS:6210Applied Survival Analysis3
BIOS:6310Introductory Longitudinal Data Analysis3
BIOS:6420Survey Design and Analysis3
BIOS:6610Statistical Methods in Clinical Trials3
BIOS:6650Causal Inference3
BIOS:6720Statistical Machine Learning for Biomedical and Public Health Data3
BIOS:6810Bayesian Methods and Design3
BIOS:7230Advanced Clinical Trials3
BIOS:7600Advanced Biostatistics Seminar0-3
BME:5320Bioinformatics Techniques3
EPID:5200Principles of Public Health Informatics3

Miscellaneous

PATH:5260Translational Histopathology3

Final Project

In addition to completion of the 30 s.h. in required course work, scholars must submit a final project. The project may be in one of the following formats.

  • A complete grant application for a K01, K08, K23, K08, R01, R03, R21, or a U.S. Department of Veterans Affairs career award. The R03 completed as part of the required grant writing course may not be submitted as the final project.
  • An original research manuscript (less than 2,500 words) of a published or in publishable quality for a peer-reviewed journal. The manuscript must contain the following components:

a structured abstract;

an introductory section that adequately frames the research question addressed; and

a methodology section that sufficiently describes the following elements (study design, study sample, data collection strategies and sources, data elements, and data analysis), results of the study, and a discussion including a description of the relationship of the current findings to prior relevant research and/or policy implications of the findings and methodological limitations.

The Translational Biomedicine Program welcomes applicants who have diverse educational and scientific backgrounds and varied research interests. Applicants must have a strong interest and background in a health science profession and knowledge of basic sciences and medicine.

Applicants must meet the admission requirements of the Graduate College; see the Manual of Rules and Regulations of the Graduate College.

Translational biomedicine applicants must:

  • have a doctoral-level degree in a biomedical discipline (e.g., M.D., D.O., D.D.S., D.N.P., Ph.D., Pharm.D., D.V.M., or the equivalent);
  • be employed by the University of Iowa as an associate professor, assistant professor, instructor, a fellow physician, or a postdoctoral scholar/fellow;
  • be engaged in scientific research with a University of Iowa mentor who has funding from a peer-reviewed source (e.g. National Institutes of Health, National Science Foundation, another foundation, and so forth);
  • hold a bachelor's degree from a regionally accredited American college or university or an equivalent degree from an international institution, as determined by the University of Iowa Office of Admissions;
  • have a g.p.a. of at least 3.00 or the international equivalent, as determined by the University of Iowa Office of Admissions; and
  • have a Graduate Record Exam (GRE) General Test combined verbal and quantitative score of 300 on the revised test (or 1050 on the old test) and an analytical writing score of 4.0 or above; applicants who already hold a graduate or professional degree may seek a waiver of the GRE requirement.

Applicants whose first language is not English must score at least 100 (internet-based) on the Test of English as a Foreign Language (TOEFL), or they must have a score of at least 7.0, with no subscore lower than 6.0, on the International English Language Testing System (IELTS).

Applicants must submit a curriculum vitae, a statement of research interest and career goals, and three letters of recommendation. One letter must be from the applicant’s UI research mentor; the program recommends that the second be a letter of support from the applicant’s department chair.

All prospective students, and their mentors, must guarantee that once they are accepted as students in the program, they will be able to devote essentially all of their time over a two-year period to training. For instance, a fellow in the Carver College of Medicine might spend no more than two months each year working on clinical assignments (e.g., two months of inpatient assignments or one month of inpatient assignments and one-half day per week in a clinic).

Sample Plan of Study

Sample plans represent one way to complete a program of study. Actual course selection and sequence will vary and should be discussed with an academic advisor. For additional sample plans, see MyUI.

Translational Biomedicine, M.S.

Plan of Study Grid (Manual)
Academic Career
Any SemesterHours
Final Project a  
 Hours0
First Year
Fall
TBM:5000 Translational Biomedical Research 3
TBM:5001 Introduction to Translational Biomedicine 3
TBM:5002 Critical Thinking and Communication: Study Design and Commercialization 1
 Hours7
Spring
TBM:5000 Translational Biomedical Research 3
TBM:5003 Critical Thinking and Communication: Scientific Writing and Presentation Strategies 1
BIOS:4120 Introduction to Biostatistics 3
EPID:6950 Clinical Research Ethics 2
 Hours9
Second Year
Fall
TBM:5004 Critical Thinking and Communication: Career Development and the Funding Process 1
EPID:4400 Epidemiology I: Principles 3
Elective course 3
 Hours7
Spring
TBM:5000 Translational Biomedical Research 3
TBM:5005 Critical Thinking and Communication: Leadership, Team Science, and Mentoring 1
Elective course 3
 Hours7
 Total Hours30